Superman for All Seasons
This was a tough one. I have more "S" comics than any other letter in my collection.. So many great characters start with the letter.
But if you want an "S" comic starring an "S" character, you could do worse than this one. The Armchair Squid is a recent comic convert and has express his...not so much disdain, but disinterest in the character of Superman.
This is the book I should have recommended to him. It is not an origin story, per se, but a fleshing out and rounding of who the character is and who he can be. Each "season" is narrated by a different supporting character from the Superman mythos, which only adds to the picture. You are never in the head of Superman himself.
And each issue is beautifully painted and colored by Tim Sale and Bjarne Hansen.
Of all the collaborations between Loeb and Sale, this is one of the best.